5XUU
Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (TCCA PAM)
Summary for 5XUU
| Entry DOI | 10.2210/pdb5xuu/pdb |
| Descriptor | LbCpf1, crRNA, DNA (29-MER), ... (8 entities in total) |
| Functional Keywords | nuclease, hydrolase-rna-dna complex, hydrolase/rna/dna |
| Biological source | Lachnospiraceae bacterium ND2006 More |
| Total number of polymer chains | 4 |
| Total formula weight | 168778.18 |
| Authors | Yamano, T.,Nishimasu, H.,Ishitani, R.,Nureki, O. (deposition date: 2017-06-26, release date: 2017-08-09, Last modification date: 2023-11-22) |
| Primary citation | Yamano, T.,Zetsche, B.,Ishitani, R.,Zhang, F.,Nishimasu, H.,Nureki, O. Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1. Mol. Cell, 67:633-645.e3, 2017 Cited by PubMed: 28781234DOI: 10.1016/j.molcel.2017.06.035 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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