5XLW
Mycobacterium tuberculosis Pantothenate kinase mutant F247A/F254A
Summary for 5XLW
Entry DOI | 10.2210/pdb5xlw/pdb |
Related | 5XLV |
Descriptor | Pantothenate kinase, 1,2-ETHANEDIOL, PENTAETHYLENE GLYCOL, ... (6 entities in total) |
Functional Keywords | homodimer, coa biosynthesis, nucleotide binding, concerted movement, structural transformation, transferase |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Total number of polymer chains | 2 |
Total formula weight | 73075.33 |
Authors | Paul, A.,Kumar, P.,Surolia, A.,Vijayan, M. (deposition date: 2017-05-11, release date: 2018-05-16, Last modification date: 2023-11-22) |
Primary citation | Paul, A.,Kumar, P.,Surolia, A.,Vijayan, M. Biochemical and structural studies of mutants indicate concerted movement of the dimer interface and ligand-binding region of Mycobacterium tuberculosis pantothenate kinase Acta Crystallogr F Struct Biol Commun, 73:635-643, 2017 Cited by PubMed: 29095158DOI: 10.1107/S2053230X17015667 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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