5XLV

Mycobacterium tuberculosis Pantothenate kinase mutant F254A

Summary for 5XLV

Entry DOI	10.2210/pdb5xlv/pdb
Related	5XLW
Descriptor	Pantothenate kinase, SULFATE ION, TETRAETHYLENE GLYCOL, ... (6 entities in total)
Functional Keywords	homodimer, coa biosynthesis, nucleotide binding, concerted movement, structural transformation, transferase
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains	2
Total formula weight	74665.08
Authors	Paul, A.,Kumar, P.,Surolia, A.,Vijayan, M. (deposition date: 2017-05-11, release date: 2018-05-16, Last modification date: 2023-11-22)
Primary citation	Paul, A.,Kumar, P.,Surolia, A.,Vijayan, M. Biochemical and structural studies of mutants indicate concerted movement of the dimer interface and ligand-binding region of Mycobacterium tuberculosis pantothenate kinase Acta Crystallogr F Struct Biol Commun, 73:635-643, 2017 Cited by PubMed: 29095158 DOI: 10.1107/S2053230X17015667 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation