5XLD

The structure of hemagglutinin Q226L-G228S mutant from an avian-origin H4N6 influenza virus in complex with human receptor analog LSTc

Summary for 5XLD

Entry DOI	10.2210/pdb5xld/pdb
Related PRD ID	PRD_900046
Descriptor	Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	h4 hemagglutinin, influenza virus, receptor binding, viral protein
Biological source	Influenza A virus (strain A/Duck/Czechoslovakia/1956 H4N6) More
Cellular location	Host apical cell membrane ; Single-pass type I membrane protein . Virion membrane ; Single-pass type I membrane protein : A3KF09 A3KF09
Total number of polymer chains	4
Total formula weight	114881.85
Authors	Song, H.,Qi, J.,Gao, F.G. (deposition date: 2017-05-10, release date: 2017-08-02, Last modification date: 2023-11-22)
Primary citation	Song, H.,Qi, J.,Xiao, H.,Bi, Y.,Zhang, W.,Xu, Y.,Wang, F.,Shi, Y.,Gao, G.F. Avian-to-Human Receptor-Binding Adaptation by Influenza A Virus Hemagglutinin H4 Cell Rep, 20:1201-1214, 2017 Cited by PubMed: 28768203 DOI: 10.1016/j.celrep.2017.07.028 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation