5XJ4
Complex structure of durvalumab-scFv/PD-L1
Summary for 5XJ4
Entry DOI | 10.2210/pdb5xj4/pdb |
Related | 5XJ3 |
Descriptor | Programmed cell death 1 ligand 1, durvalumab-VH, durvalumab-VL, ... (4 entities in total) |
Functional Keywords | durvalumab, pd-l1, complex structure, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Isoform 1: Cell membrane ; Single-pass type I membrane protein . Isoform 2: Endomembrane system ; Single-pass type I membrane protein : Q9NZQ7 |
Total number of polymer chains | 3 |
Total formula weight | 51092.38 |
Authors | |
Primary citation | Tan, S.,Liu, K.,Chai, Y.,Zhang, C.W.,Gao, S.,Gao, G.F.,Qi, J. Distinct PD-L1 binding characteristics of therapeutic monoclonal antibody durvalumab Protein Cell, 9:135-139, 2018 Cited by PubMed: 28488247DOI: 10.1007/s13238-017-0412-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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