5XE9
Crystal Structure of the Complex of the Peptidase Domain of Streptococcus mutans ComA with a Small Molecule Inhibitor.
Summary for 5XE9
Entry DOI | 10.2210/pdb5xe9/pdb |
Related | 5XE8 |
Descriptor | Putative ABC transporter, ATP-binding protein ComA, [(1~{S},2~{R},4~{S},5~{R})-5-[5-(4-methoxyphenyl)-2-methyl-pyrazol-3-yl]-1-azabicyclo[2.2.2]octan-2-yl]methyl ~{N}-propylcarbamate (3 entities in total) |
Functional Keywords | peptidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Streptococcus mutans serotype c |
Total number of polymer chains | 2 |
Total formula weight | 35120.18 |
Authors | Ishii, S.,Fukui, K.,Yokoshima, S.,Kumagai, K.,Beniyama, Y.,Kodama, T.,Fukuyama, T.,Okabe, T.,Nagano, T.,Kojima, H.,Yano, T. (deposition date: 2017-04-03, release date: 2017-06-28, Last modification date: 2023-11-22) |
Primary citation | Ishii, S.,Fukui, K.,Yokoshima, S.,Kumagai, K.,Beniyama, Y.,Kodama, T.,Fukuyama, T.,Okabe, T.,Nagano, T.,Kojima, H.,Yano, T. High-throughput Screening of Small Molecule Inhibitors of the Streptococcus Quorum-sensing Signal Pathway Sci Rep, 7:4029-4029, 2017 Cited by PubMed: 28642545DOI: 10.1038/s41598-017-03567-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.101 Å) |
Structure validation
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