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5X7B

Crystal structure of SHP2_SH2-CagA EPIYA_C peptide complex

Summary for 5X7B
Entry DOI10.2210/pdb5x7b/pdb
Related5X7C
DescriptorTyrosine-protein phosphatase non-receptor type 11, CagA (3 entities in total)
Functional Keywordshelicobacter pylori caga, sh2 domain-containing protein tyrosine phosphatase 2 (shp2), caga polymorphism, hydrolase
Biological sourceHomo sapiens (Human)
More
Cellular locationCytoplasm : Q06124
Total number of polymer chains3
Total formula weight27844.00
Authors
Senda, M.,Senda, T. (deposition date: 2017-02-24, release date: 2017-09-13, Last modification date: 2023-11-22)
Primary citationHayashi, T.,Senda, M.,Suzuki, N.,Nishikawa, H.,Ben, C.,Tang, C.,Nagase, L.,Inoue, K.,Senda, T.,Hatakeyama, M.
Differential Mechanisms for SHP2 Binding and Activation Are Exploited by Geographically Distinct Helicobacter pylori CagA Oncoproteins.
Cell Rep, 20:2876-2890, 2017
Cited by
PubMed: 28930683
DOI: 10.1016/j.celrep.2017.08.080
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.45 Å)
Structure validation

217705

數據於2024-03-27公開中

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