5WZ4

Crystal structure of Mycobacterium tuberculosis VapC20 (Rv2549c), Sarcin-Ricin loop cleaving toxin

Summary for 5WZ4

• Entry DOI: 10.2210/pdb5wz4/pdb
• Related: 5WZF
• Descriptor: 23S rRNA-specific endonuclease VapC20 (2 entities in total)
• Functional Keywords: vapc toxin, toxin-antitoxin system, sarcin-ricin loop cleaving toxin, pin-domain, homodimer, hydrolase
• Biological source: Mycobacterium tuberculosis H37Rv
• Total number of polymer chains: 2
• Total formula weight: 32371.28

Authors

Thakur, K.G.,Deep, A. (deposition date: 2017-01-17, release date: 2017-10-25, Last modification date: 2023-03-01)

• Primary citation: Deep, A.,Kaundal, S.,Agarwal, S.,Singh, R.,Thakur, K.G.; Crystal structure of Mycobacterium tuberculosis VapC20 toxin and its interactions with cognate antitoxin, VapB20, suggest a model for toxin-antitoxin assembly.; FEBS J., 284:4066-4082, 2017; PubMed: 28986943; DOI: 10.1111/febs.14289

Experimental method

X-RAY DIFFRACTION (1.775 Å)