5WTH

Cryo-EM structure for Hepatitis A virus complexed with FAB

Summary for 5WTH

• Entry DOI: 10.2210/pdb5wth/pdb
• Related: 5WTE 5WTF
• EMDB information: 6686 6687 6688
• Descriptor: Polyprotein, VP2, VP3, ... (5 entities in total)
• Functional Keywords: hav, neutralizing mechanism, receptor recognition, viral entry, virus
• Biological source: Hepatovirus A; More
• Total number of polymer chains: 5
• Total formula weight: 130512.68

Authors

Wang, X.,Zhu, L.,Dang, M.,Hu, Z.,Gao, Q.,Yuan, S.,Sun, Y.,Zhang, B.,Ren, J.,Walter, T.S.,Wang, J.,Fry, E.E.,Stuart, D.I.,Rao, Z. (deposition date: 2016-12-12, release date: 2017-01-25, Last modification date: 2019-11-06)

• Primary citation: Wang, X.,Zhu, L.,Dang, M.,Hu, Z.,Gao, Q.,Yuan, S.,Sun, Y.,Zhang, B.,Ren, J.,Kotecha, A.,Walter, T.S.,Wang, J.,Fry, E.E.,Stuart, D.I.,Rao, Z.; Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site; Proc. Natl. Acad. Sci. U.S.A., 114:770-775, 2017; PubMed: 28074040; DOI: 10.1073/pnas.1616502114

Experimental method

ELECTRON MICROSCOPY (4.2 Å)