5WNL

Crystal structure of murine receptor-interacting protein 4 (Ripk4) D143N bound to staurosporine

Summary for 5WNL

Entry DOI	10.2210/pdb5wnl/pdb
Related	5WNI 5WNJ 5WNK 5WNM
Descriptor	Receptor-interacting serine/threonine-protein kinase 4, STAUROSPORINE, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	kinase, inhibitor, complex, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Mus musculus (Mouse)
Cellular location	Cytoplasm: Q9ERK0
Total number of polymer chains	1
Total formula weight	39490.02
Authors	Huang, C.S.,Hymowitz, S.G. (deposition date: 2017-08-01, release date: 2018-05-09, Last modification date: 2024-03-13)
Primary citation	Huang, C.S.,Oberbeck, N.,Hsiao, Y.C.,Liu, P.,Johnson, A.R.,Dixit, V.M.,Hymowitz, S.G. Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity. Structure, 26:767-, 2018 Cited by PubMed: 29706531 DOI: 10.1016/j.str.2018.04.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation