5WMP

Crystal Structure of HLA-B7 in complex with TPR, a CMV peptide

5WMP の概要

• エントリーDOI: 10.2210/pdb5wmp/pdb
• 分子名称: HLA class I histocompatibility antigen, B-7 alpha chain, Beta-2-microglobulin, TPR peptide from CMV, ... (9 entities in total)
• 機能のキーワード: hla, viral peptide, iav, ebv, cmv, crossreactivity, tcr, t cell, heterologous immunity, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 45670.44

構造登録者

Gras, S.,Rossjohn, J. (登録日: 2017-07-30, 公開日: 2018-06-06, 最終更新日: 2018-06-13)

• 主引用文献: Rowntree, L.C.,Nguyen, T.H.O.,Halim, H.,Purcell, A.W.,Rossjohn, J.,Gras, S.,Kotsimbos, T.C.,Mifsud, N.A.; Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses.; J. Immunol., 200:3993-4003, 2018; PubMed: 29735483; DOI: 10.4049/jimmunol.1800010

実験手法

X-RAY DIFFRACTION (1.6 Å)