5WM2

Crystal Structure of CahJ in Complex with Salicylic Acid and AMP

5WM2 の概要

• エントリーDOI: 10.2210/pdb5wm2/pdb
• 分子名称: Salicylate-AMP ligase, 2-HYDROXYBENZOIC ACID, ADENOSINE MONOPHOSPHATE, ... (6 entities in total)
• 機能のキーワード: ligase, adenylation domain, peptide synthetase
• 由来する生物種: Streptomyces gandocaensis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 61512.10

構造登録者

Sikkema, A.P.,Smith, J.L. (登録日: 2017-07-28, 公開日: 2018-05-23, 最終更新日: 2023-10-04)

• 主引用文献: Tripathi, A.,Park, S.R.,Sikkema, A.P.,Cho, H.J.,Wu, J.,Lee, B.,Xi, C.,Smith, J.L.,Sherman, D.H.; A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ.; Chembiochem, 19:1595-1600, 2018; PubMed: 29742306; DOI: 10.1002/cbic.201800233

実験手法

X-RAY DIFFRACTION (1.548 Å)