5WIQ
Crystal structure of the segment, GFNGGFG, from the low complexity domain of TDP-43, residues 396-402
Summary for 5WIQ
| Entry DOI | 10.2210/pdb5wiq/pdb |
| Descriptor | TAR DNA-binding protein 43 (2 entities in total) |
| Functional Keywords | amyloid, larks, tdp-43, protein fibril |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 1309.35 |
| Authors | Guenther, E.L.,Sawaya, M.R.,Eisenberg, D.S. (deposition date: 2017-07-19, release date: 2018-04-18, Last modification date: 2023-10-04) |
| Primary citation | Guenther, E.L.,Cao, Q.,Trinh, H.,Lu, J.,Sawaya, M.R.,Cascio, D.,Boyer, D.R.,Rodriguez, J.A.,Hughes, M.P.,Eisenberg, D.S. Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25:463-471, 2018 Cited by PubMed: 29786080DOI: 10.1038/s41594-018-0064-2 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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