5WII

TraE protein in complex with 2-Chloroisonicotinic Acid

5WII の概要

• エントリーDOI: 10.2210/pdb5wii/pdb
• 分子名称: Conjugal transfer protein, 2-chloropyridine-4-carboxylic acid (3 entities in total)
• 機能のキーワード: type iv secretion system, fragment-based drug design, complex, inhibitor, antimicrobial resistance, bacterial secretion, virb, protein transport
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 75429.97

構造登録者

Casu, B.,Arya, T.,Bessette, B.,Baron, C. (登録日: 2017-07-19, 公開日: 2017-11-15, 最終更新日: 2023-10-04)

• 主引用文献: Casu, B.,Arya, T.,Bessette, B.,Baron, C.; Fragment-based screening identifies novel targets for inhibitors of conjugative transfer of antimicrobial resistance by plasmid pKM101.; Sci Rep, 7:14907-14907, 2017; PubMed: 29097752; DOI: 10.1038/s41598-017-14953-1

実験手法

X-RAY DIFFRACTION (2.79 Å)