5WDH

Motor domain of human kinesin family member C1

Replaces:  2REP

Summary for 5WDH

DescriptorKinesin-like protein KIFC1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywordskinesin, structural genomics consortium, motor domain, adp, sgc, motor protein
Biological sourceHomo sapiens (Human)
Cellular locationNucleus  Q9BW19
Total number of polymer chains1
Total molecular weight41030.12
Authors
Zhu, H.,Tempel, W.,He, H.,Shen, Y.,Wang, J.,Brothers, G.,Landry, R.,Arrowsmith, C.H.,Edwards, A.M.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2017-07-05, release date: 2017-08-09, Last modification date: 2017-12-20)
Primary citation
Park, H.W.,Ma, Z.,Zhu, H.,Jiang, S.,Robinson, R.C.,Endow, S.A.
Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein.
Sci Rep, 7:15121-15121, 2017
PubMed: 29123223 (PDB entries with the same primary citation)
DOI: 10.1038/s41598-017-14754-6
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.248 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.273101.0%4.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution