5WDE

Crystal structure of the KIFC3 motor domain in complex with ADP

Replaces:  2H58

Summary for 5WDE

• Entry DOI: 10.2210/pdb5wde/pdb
• Descriptor: Kinesin-like protein KIFC3, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: kinesin, motor domain, adp, structural genomics, structur al genomics consortium, sgc, structural genomics consortium, motor protein
• Biological source: Homo sapiens (Human)
• Cellular location: Cell junction, adherens junction : Q9BVG8
• Total number of polymer chains: 1
• Total formula weight: 36673.03

Authors

Shen, Y.,Tempel, W.,Landry, R.,Arrowsmith, C.H.,Edwards, A.M.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2017-07-05, release date: 2017-08-09, Last modification date: 2023-10-04)

• Primary citation: Park, H.W.,Ma, Z.,Zhu, H.,Jiang, S.,Robinson, R.C.,Endow, S.A.; Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein.; Sci Rep, 7:15121-15121, 2017; PubMed: 29123223; DOI: 10.1038/s41598-017-14754-6

Experimental method

X-RAY DIFFRACTION (1.85 Å)