5WCD

Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 04-1D02 Fab.

5WCD の概要

• エントリーDOI: 10.2210/pdb5wcd/pdb
• 分子名称: VRC315 04-1D02 Fab Heavy chain, VRC315 04-1D02 Fab Light chain, PHOSPHATE ION, ... (5 entities in total)
• 機能のキーワード: immune system, antibody, influenza, human vaccine trial
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 47718.07

構造登録者

Joyce, M.G.,Andrews, S.F.,Mascola, J.R.,McDermott, A.B.,Kwong, P.D. (登録日: 2017-06-29, 公開日: 2017-08-23, 最終更新日: 2018-11-28)

• 主引用文献: Andrews, S.F.,Joyce, M.G.,Chambers, M.J.,Gillespie, R.A.,Kanekiyo, M.,Leung, K.,Yang, E.S.,Tsybovsky, Y.,Wheatley, A.K.,Crank, M.C.,Boyington, J.C.,Prabhakaran, M.S.,Narpala, S.R.,Chen, X.,Bailer, R.T.,Chen, G.,Coates, E.,Kwong, P.D.,Koup, R.A.,Mascola, J.R.,Graham, B.S.,Ledgerwood, J.E.,McDermott, A.B.; Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans.; Sci Immunol, 2:-, 2017; PubMed: 28783708; DOI: 10.1126/sciimmunol.aan2676

実験手法

X-RAY DIFFRACTION (1.814 Å)