5W9E

Toxoplasma Gondii CDPK1 in complex with inhibitor GXJ-186

Summary for 5W9E

• Entry DOI: 10.2210/pdb5w9e/pdb
• Descriptor: Calmodulin-domain protein kinase 1, 1-tert-butyl-3-[(3-chlorophenyl)sulfanyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine (3 entities in total)
• Functional Keywords: cdpk, parasitology, atp-binding, kinase, nucleotide-binding, serine/threonine-protein kinase, transferase, structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Toxoplasma gondii
• Total number of polymer chains: 1
• Total formula weight: 55560.75

Authors

El Bakkouri, M.,Lovato, D.,Loppnau, P.,Lin, Y.H.,Rutaganaria, F.,Lopez, M.S.,Shokat, L.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Sibley, D.,Hui, R.,Walker, J.R. (deposition date: 2017-06-23, release date: 2017-08-02, Last modification date: 2024-03-13)

• Primary citation: El Bakkouri, M.,Lovato, D.,Loppnau, P.,Lin, Y.H.,Rutaganaria, F.,Lopez, M.S.,Shokat, L.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Sibley, D.,Hui, R.,Walker, J.R.; Toxoplasma Gondii CDPK1 in complex with inhibitor GXJ-186; To be published,

Experimental method

X-RAY DIFFRACTION (2.44 Å)