5W6R

Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with cyclic peptide CP141099 (P6)

Summary for 5W6R

• Entry DOI: 10.2210/pdb5w6r/pdb
• Related: 5W5S 5W5U 5W6I 5W6T 5W6U
• Descriptor: Hemagglutinin, ACE-PH8-ORN-LEU-GLU-TYR-PHE-GLU-TRP-LEU-SER-9WV, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: glycoprotein, ectodomain, n-glycosylation, viral protein, viral protein-peptide complex, viral protein/peptide
• Biological source: Influenza A virus (A/Puerto Rico/8/1934(H1N1)); More
• Total number of polymer chains: 12
• Total formula weight: 239439.55

Authors

Wilson, I.A.,Kadam, R.U. (deposition date: 2017-06-16, release date: 2017-10-04, Last modification date: 2023-11-15)

• Primary citation: Kadam, R.U.,Juraszek, J.,Brandenburg, B.,Buyck, C.,Schepens, W.B.G.,Kesteleyn, B.,Stoops, B.,Vreeken, R.J.,Vermond, J.,Goutier, W.,Tang, C.,Vogels, R.,Friesen, R.H.E.,Goudsmit, J.,van Dongen, M.J.P.,Wilson, I.A.; Potent peptidic fusion inhibitors of influenza virus.; Science, 358:496-502, 2017; PubMed: 28971971; DOI: 10.1126/science.aan0516

Experimental method

X-RAY DIFFRACTION (2.731 Å)