5W4H

X-ray crystallographic structure of a beta-hairpin peptide mimic derived from Abeta 16-36. Synchrotron data set. (ORN)KLV(MEA)FAE(ORN)AIIGLMV.

5W4H の概要

• エントリーDOI: 10.2210/pdb5w4h/pdb
• 分子名称: A-beta 17_36 peptide: ORN-LYS-LEU-VAL-MEA-PHE-ALA-GLU-ORN-ALA-ILE-ILE-GLY-LEU-MET-VAL (2 entities in total)
• 機能のキーワード: amyloid, oligomer, alzheimer's, trimer, protein fibril, de novo protein
• 由来する生物種: Homo sapiens
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 5382.81

構造登録者

Kreutzer, A.G.,Spencer, R.K.,Nowick, J.S. (登録日: 2017-06-11, 公開日: 2017-11-22, 最終更新日: 2023-10-04)

• 主引用文献: Kreutzer, A.G.,Spencer, R.K.,McKnelly, K.J.,Yoo, S.,Hamza, I.L.,Salveson, P.J.,Nowick, J.S.; A Hexamer of a Peptide Derived from A beta 16-36.; Biochemistry, 56:6061-6071, 2017; PubMed: 29028351; DOI: 10.1021/acs.biochem.7b00831

実験手法

X-RAY DIFFRACTION (1.718 Å)