5W27

Crystal structure of TnmS3 in complex with tiancimycin (TNM B)

5W27 の概要

• エントリーDOI: 10.2210/pdb5w27/pdb
• 関連するPDBエントリー: 5W29
• 分子名称: Glyoxalase/bleomycin resisance protein/dioxygenase, methyl (2E)-3-[(1aS,11S,11aS,14Z,18R)-3,18-dihydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]but-2-enoate (3 entities in total)
• 機能のキーワード: glyoxalase/bleomycin resistance protein/dioxygenase superfamily, structural genomics, psi-biology, midwest center for structural genomics, mcsg, enzyme discovery for natural product biosynthesis, natpro, lyase, biosynthetic protein, tiancimycin-binding protein
• 由来する生物種: Streptomyces sp. CB03234
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32017.58

構造登録者

Chang, C.Y.,Chang, C.,Nocek, B.,Rudolf, J.D.,Joachimiak, A.,Phillips Jr., G.N.,SHen, B.,Enzyme Discovery for Natural Product Biosynthesis (NatPro),Midwest Center for Structural Genomics (MCSG) (登録日: 2017-06-05, 公開日: 2018-06-06, 最終更新日: 2023-10-04)

• 主引用文献: Chang, C.Y.,Chang, C.,Nocek, B.,Rudolf, J.D.,Joachimiak, A.,Phillips, G.N.,SHen, B.,Enzyme Discovery for Natural Product Biosynthesis (NatPro),Midwest Center for Structural Genomics (MCSG); Crystal structure of TnmS3 in complex with tiancimycin (TNM B); To Be Published,

実験手法

X-RAY DIFFRACTION (1.8 Å)