5W06
HUMAN TISSUE FACTOR IN COMPLEX WITH ANTIBODY M1587
Summary for 5W06
Entry DOI | 10.2210/pdb5w06/pdb |
Related | 4m7k 4m7l 5W06 |
Descriptor | Tissue factor, M1587 FAB LIGHT CHAIN, M1587 FAB HEAVY CHAIN, ... (5 entities in total) |
Functional Keywords | immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Isoform 1: Membrane ; Single-pass type I membrane protein . Isoform 2: Secreted : P13726 |
Total number of polymer chains | 3 |
Total formula weight | 73396.75 |
Authors | Teplyakov, A.,Obmolova, G.,Malia, T.J.,Gilliland, G.L. (deposition date: 2017-05-30, release date: 2017-06-14, Last modification date: 2023-10-04) |
Primary citation | Teplyakov, A.,Obmolova, G.,Malia, T.J.,Raghunathan, G.,Martinez, C.,Fransson, J.,Edwards, W.,Connor, J.,Husovsky, M.,Beck, H.,Chi, E.,Fenton, S.,Zhou, H.,Almagro, J.C.,Gilliland, G.L. Structural insights into humanization of anti-tissue factor antibody 10H10. MAbs, 10:269-277, 2018 Cited by PubMed: 29283291DOI: 10.1080/19420862.2017.1412026 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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