5VQJ

Discovery of a first GH11 exo-1,4-beta-xylanase from a diverse microbial sugar cane bagasse composting community

Summary for 5VQJ

• Entry DOI: 10.2210/pdb5vqj/pdb
• Descriptor: exo-beta-1,4-xylanase (2 entities in total)
• Functional Keywords: beta-jelly roll, hydrolase
• Biological source: unidentified
• Total number of polymer chains: 1
• Total formula weight: 24537.00

Authors

Mello, B.L.,Polikarpov, I. (deposition date: 2017-05-09, release date: 2018-03-21, Last modification date: 2023-10-04)

Primary citation

Mello, B.L.,Alessi, A.M.,Riano-Pachon, D.M.,deAzevedo, E.R.,Guimaraes, F.E.G.,Espirito Santo, M.C.,McQueen-Mason, S.,Bruce, N.C.,Polikarpov, I.
Targeted metatranscriptomics of compost-derived consortia reveals a GH11 exerting an unusual exo-1,4-beta-xylanase activity.
Biotechnol Biofuels, 10:254-254, 2017

PubMed Abstract: Using globally abundant crop residues as a carbon source for energy generation and renewable chemicals production stand out as a promising solution to reduce current dependency on fossil fuels. In nature, such as in compost habitats, microbial communities efficiently degrade the available plant biomass using a diverse set of synergistic enzymes. However, deconstruction of lignocellulose remains a challenge for industry due to recalcitrant nature of the substrate and the inefficiency of the enzyme systems available, making the economic production of lignocellulosic biofuels difficult. Metatranscriptomic studies of microbial communities can unveil the metabolic functions employed by lignocellulolytic consortia and identify novel biocatalysts that could improve industrial lignocellulose conversion.

PubMed: 29118851
DOI: 10.1186/s13068-017-0944-4

Experimental method

X-RAY DIFFRACTION (1.761 Å)