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5VPZ

Crystal structure of human KRAS G12A mutant in complex with GTP-gamma-S

Summary for 5VPZ
Entry DOI10.2210/pdb5vpz/pdb
Related5VP7 5VPI 5VPY 5VQ0 5VQ1 5VQ2 5VQ6 5VQ8
DescriptorGTPase KRas, MAGNESIUM ION, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ... (4 entities in total)
Functional Keywordsoncogenic mutant, hydrolase
Biological sourceHomo sapiens (Human)
Cellular locationCell membrane ; Lipid-anchor ; Cytoplasmic side : P01116
Total number of polymer chains2
Total formula weight39942.84
Authors
Xu, S.,Long, B.,Boris, G.,Ni, S.,Kennedy, M.A. (deposition date: 2017-05-06, release date: 2017-12-06, Last modification date: 2024-03-13)
Primary citationXu, S.,Long, B.N.,Boris, G.H.,Chen, A.,Ni, S.,Kennedy, M.A.
Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.
Acta Crystallogr D Struct Biol, 73:970-984, 2017
Cited by
PubMed: 29199977
DOI: 10.1107/S2059798317015418
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

217705

數據於2024-03-27公開中

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