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5VDB

Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with bisubstrate analog 3

5VDB の概要
エントリーDOI10.2210/pdb5vdb/pdb
関連するPDBエントリー4L8A 5VD6
分子名称acetyltransferase PA4794, SULFATE ION, (3R,5S,9R,26S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14,20-trioxo-26-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15,21-triaza-3,5-diphosphaheptacosan-27-oic acid 3,5-dioxide (non-preferred name), ... (4 entities in total)
機能のキーワードgnat, acetyltransferase, bisubstrate inhibitor, structural genomics, psi-biology, midwest center for structural genomics, mcsg, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
由来する生物種Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
タンパク質・核酸の鎖数1
化学式量合計19608.79
構造登録者
Majorek, K.A.,Joachimiak, A.,Minor, W.,Midwest Center for Structural Genomics (MCSG) (登録日: 2017-04-01, 公開日: 2017-07-26, 最終更新日: 2023-10-04)
主引用文献Reidl, C.,Majorek, K.A.,Dang, J.,Tran, D.,Jew, K.,Law, M.,Payne, Y.,Minor, W.,Becker, D.P.,Kuhn, M.L.
Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases.
FEBS Lett., 591:2348-2361, 2017
Cited by
PubMed: 28703494
DOI: 10.1002/1873-3468.12753
主引用文献が同じPDBエントリー
実験手法
X-RAY DIFFRACTION (1.4 Å)
構造検証レポート
Validation report summary of 5vdb
検証レポート(詳細版)ダウンロードをダウンロード

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件を2024-07-10に公開中

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