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5VBT

Crystal structure of a highly specific and potent USP7 ubiquitin variant inhibitor

Summary for 5VBT
Entry DOI10.2210/pdb5vbt/pdb
DescriptorUBH04 (2 entities in total)
Functional Keywordsubiquitin, inhibitor, structural genomics, structural genomics consortium, sgc, de novo protein
Biological sourcesynthetic construct
Total number of polymer chains2
Total formula weight17752.58
Authors
DONG, A.,DONG, X.,LIU, L.,GUO, Y.,LI, Y.,ZHANG, W.,WALKER, J.R.,SIDHU, S.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,TONG, Y.,Structural Genomics Consortium (SGC) (deposition date: 2017-03-30, release date: 2017-06-07, Last modification date: 2023-10-04)
Primary citationDONG, X.,DONG, A.,LIU, L.,GUO, Y.,LI, Y.,ZHANG, W.,WALKER, J.R.,SIDHU, S.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,TONG, Y.,Structural Genomics Consortium (SGC)
Crystal structure of a highly specific and potent USP7 ubiquitin variant inhibitor
to be published,
Experimental method
X-RAY DIFFRACTION (1.51 Å)
Structure validation

227344

数据于2024-11-13公开中

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