5VAG

Crystal structure of H7-specific antibody m826 in complex with the HA1 domain of hemagglutinin from H7N9 influenza virus

5VAG の概要

• エントリーDOI: 10.2210/pdb5vag/pdb
• 分子名称: Hemagglutinin, Light chain of antibody m826, Heavy chain of antibody m826, ... (5 entities in total)
• 機能のキーワード: hemagglutinin, h7n9, immune system
• 由来する生物種: Influenza A virus; 詳細
• 細胞内の位置: Host apical cell membrane ; Single-pass type I membrane protein . Virion membrane ; Single-pass type I membrane protein : R4NN21
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 85349.31

構造登録者

Song, H.,Ying, T.,Ji, X. (登録日: 2017-03-26, 公開日: 2017-12-20, 最終更新日: 2023-10-04)

• 主引用文献: Yu, F.,Song, H.,Wu, Y.,Chang, S.Y.,Wang, L.,Li, W.,Hong, B.,Xia, S.,Wang, C.,Khurana, S.,Feng, Y.,Wang, Y.,Sun, Z.,He, B.,Hou, D.,Manischewitz, J.,King, L.R.,Song, Y.,Min, J.Y.,Golding, H.,Ji, X.,Lu, L.,Jiang, S.,Dimitrov, D.S.,Ying, T.; A Potent Germline-like Human Monoclonal Antibody Targets a pH-Sensitive Epitope on H7N9 Influenza Hemagglutinin.; Cell Host Microbe, 22:471-483.e5, 2017; PubMed: 28966056; DOI: 10.1016/j.chom.2017.08.011

実験手法

X-RAY DIFFRACTION (1.9 Å)