5V7Z

SSNMR Structure of the Human RIP1/RIP3 Necrosome

Summary for 5V7Z

• Entry DOI: 10.2210/pdb5v7z/pdb
• NMR Information: BMRB: 30273
• Descriptor: PRO-LEU-VAL-ASN-ILE-TYR-ASN-CYS-SER-GLY-VAL-GLN-VAL-GLY-ASP, THR-ILE-TYR-ASN-SER-THR-GLY-ILE-GLN-ILE-GLY-ALA-TYR-ASN-TYR-MET-GLU-ILE (2 entities in total)
• Functional Keywords: signaling complex, human functional amyloid, signaling protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 8
• Total formula weight: 14516.15

Authors

Mompean, M.,Li, W.,Li, J.,Laage, S.,Siemer, A.B.,Wu, H.,McDermott, A.E. (deposition date: 2017-03-21, release date: 2018-03-28, Last modification date: 2019-04-10)

• Primary citation: Mompean, M.,Li, W.,Li, J.,Laage, S.,Siemer, A.B.,Bozkurt, G.,Wu, H.,McDermott, A.E.; The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex.; Cell, 173:1244-1253.e10, 2018; PubMed: 29681455; DOI: 10.1016/j.cell.2018.03.032

Experimental method

SOLID-STATE NMR