Solution structure of VKK38 bound to plasminogen kringle 2

Summary for 5V4U

Related2KJ4 5V4Z
DescriptorM protein (1 entity in total)
Functional Keywordsblood clotting, protein/peptide
Biological sourceStreptococcus pyogenes
Total number of polymer chains1
Total molecular weight4892.36
Yuan, Y.,Castellino, F. (deposition date: 2017-03-10, release date: 2017-07-26, Last modification date: 2017-09-20)
Primary citation
Yuan, Y.,Zajicek, J.,Qiu, C.,Chandrahas, V.,Lee, S.W.,Ploplis, V.A.,Castellino, F.J.
Conformationally organized lysine isosteres in Streptococcus pyogenes M protein mediate direct high-affinity binding to human plasminogen.
J. Biol. Chem., 292:15016-15027, 2017
PubMed: 28724633 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M117.794198
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers701.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures