5UUI
Crystal Structure of Spin-Labeled T77C TNFa
Summary for 5UUI
Entry DOI | 10.2210/pdb5uui/pdb |
Descriptor | Tumor necrosis factor, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate (3 entities in total) |
Functional Keywords | t77c, tnfa, tnf alpha, cytokine, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane ; Single-pass type II membrane protein . Tumor necrosis factor, membrane form: Membrane; Single-pass type II membrane protein. Tumor necrosis factor, soluble form: Secreted. C-domain 1: Secreted. C-domain 2: Secreted: P01375 |
Total number of polymer chains | 1 |
Total formula weight | 17724.16 |
Authors | Horanyi, P.S.,Dranow, D.M.,Ceska, T. (deposition date: 2017-02-16, release date: 2017-08-02, Last modification date: 2024-01-17) |
Primary citation | Carrington, B.,Myers, W.K.,Horanyi, P.,Calmiano, M.,Lawson, A.D.G. Natural Conformational Sampling of Human TNF alpha Visualized by Double Electron-Electron Resonance. Biophys. J., 113:371-380, 2017 Cited by PubMed: 28746848DOI: 10.1016/j.bpj.2017.06.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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