5UTR

Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to (3S,4R,5R,6S)-3-butyryl-4,5,6-trihydroxyazepane

Summary for 5UTR

Entry DOI	10.2210/pdb5utr/pdb
Related	4G6C 4GNV 4MSS
Descriptor	Beta-hexosaminidase, N-[(3S,4R,5R,6S)-4,5,6-trihydroxyazepan-3-yl]butanamide (3 entities in total)
Functional Keywords	glycoside hydrolase, family 3, nagz, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Burkholderia cenocepacia
Cellular location	Cytoplasm : A0A125HFC0
Total number of polymer chains	2
Total formula weight	76698.09
Authors	Vadlamani, G.,Mark, B.L. (deposition date: 2017-02-15, release date: 2017-04-19, Last modification date: 2023-10-04)
Primary citation	Vadlamani, G.,Stubbs, K.A.,Desire, J.,Bleriot, Y.,Vocadlo, D.J.,Mark, B.L. Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress beta-lactam antibiotic resistance. Protein Sci., 26:1161-1170, 2017 Cited by PubMed: 28370529 DOI: 10.1002/pro.3166 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation