5UPS

Acyl-CoA synthetase PtmA2 from Streptomyces platensis in complex with SBNP663 ligand

5UPS の概要

• エントリーDOI: 10.2210/pdb5ups/pdb
• 関連するPDBエントリー: 5E7Q 5UPQ 5UPT
• 分子名称: Acyl-CoA synthetase PtmA2, 5'-O-[(R)-hydroxy{[(7beta,8alpha,9beta,10alpha,11beta,13alpha)-7-hydroxy-19-oxo-11,16-epoxykauran-19-yl]oxy}phosphoryl]adenosine, SODIUM ION, ... (5 entities in total)
• 機能のキーワード: acyl-coa synthetase, ptma2, structural genomics, apc109894, psi-biology, midwest center for structural genomics, mcsg, enzyme discovery for natural product biosynthesis, natpro, transferase
• 由来する生物種: Streptomyces platensis subsp. rosaceus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 116769.16

構造登録者

Osipiuk, J.,Hatzos-Skintges, C.,Endres, M.,Babnigg, G.,Rudolf, J.D.,Chang, C.-Y.,Ma, M.,Shen, B.,Phillips Jr., G.N.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Enzyme Discovery for Natural Product Biosynthesis (NatPro) (登録日: 2017-02-03, 公開日: 2017-02-22, 最終更新日: 2023-11-15)

• 主引用文献: Wang, N.,Rudolf, J.D.,Dong, L.B.,Osipiuk, J.,Hatzos-Skintges, C.,Endres, M.,Chang, C.Y.,Babnigg, G.,Joachimiak, A.,Phillips, G.N.,Shen, B.; Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme.; Nat. Chem. Biol., 14:730-737, 2018; PubMed: 29867143; DOI: 10.1038/s41589-018-0061-0

実験手法

X-RAY DIFFRACTION (2.05 Å)