5UNJ

Structure of Human Liver Receptor Homolog 1 in complex with PGC1a and RJW100

Summary for 5UNJ

• Entry DOI: 10.2210/pdb5unj/pdb
• Descriptor: Nuclear receptor subfamily 5 group A member 2, Peroxisome proliferator-activated gamma coactivator 1-alpha, (1R,3aR,6aR)-5-hexyl-4-phenyl-3a-(1-phenylethenyl)-1,2,3,3a,6,6a-hexahydropentalen-1-ol, ... (4 entities in total)
• Functional Keywords: nuclear receptor, agonist, coregulator, nuclear protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 30241.12

Authors

Mays, S.G.,Ortlund, E.A. (deposition date: 2017-01-31, release date: 2017-04-19, Last modification date: 2023-10-04)

• Primary citation: Mays, S.G.,Okafor, C.D.,Tuntland, M.L.,Whitby, R.J.,Dharmarajan, V.,Stec, J.,Griffin, P.R.,Ortlund, E.A.; Structure and Dynamics of the Liver Receptor Homolog 1-PGC1 alpha Complex.; Mol. Pharmacol., 92:1-11, 2017; PubMed: 28363985; DOI: 10.1124/mol.117.108514

Experimental method

X-RAY DIFFRACTION (1.959 Å)