5UMP

Crystal structure of TnmS3, an antibiotic binding protein from Streptomyces sp. CB03234

Summary for 5UMP

Entry DOI	10.2210/pdb5ump/pdb
Descriptor	Glyoxalase/bleomycin resisance protein/dioxygenase (2 entities in total)
Functional Keywords	glyoxalase/bleomycin resistance protein/dioxygenase superfamily, structural genomics, psi-2, protein structure initiative, midwest center for structural genomics, mcsg, enzyme discovery for natural product biosynthesis, natpro, tiancimycin-binding protein
Biological source	Streptomyces sp. CB03234
Total number of polymer chains	2
Total formula weight	30305.85
Authors	Chang, C.Y.,Chang, C.,Nocek, B.,Rudolf, J.D.,Joachimiak, A.,Phillips Jr., G.N.,Shen, B.,Enzyme Discovery for Natural Product Biosynthesis (NatPro),Midwest Center for Structural Genomics (MCSG) (deposition date: 2017-01-29, release date: 2018-07-04, Last modification date: 2023-10-04)
Primary citation	Chang, C.Y.,Yan, X.,Crnovcic, I.,Annaval, T.,Chang, C.,Nocek, B.,Rudolf, J.D.,Yang, D.,Babnigg, G.,Joachimiak, A.,Phillips Jr., G.N.,Shen, B. Resistance to Enediyne Antitumor Antibiotics by Sequestration. Cell Chem Biol, 25:1075-1085.e4, 2018 Cited by PubMed: 29937405 DOI: 10.1016/j.chembiol.2018.05.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.08 Å)

Structure validation