5UBK

Inactive S1A/N269D-cpPvdQ mutant in complex with the pyoverdine precursor PVDIq reveals a specific binding pocket for the D-Tyr of this substrate

Summary for 5UBK

• Entry DOI: 10.2210/pdb5ubk/pdb
• Related: 5UBL
• Descriptor: Acyl-homoserine lactone acylase PvdQ, N-[(1R)-1-{(6S)-6-[(2-amino-2-oxoethyl)carbamoyl]-1,4,5,6-tetrahydropyrimidin-2-yl}-2-(4-hydroxyphenyl)ethyl]-N~2~-tetradecanoyl-L-glutamine (3 entities in total)
• Functional Keywords: cppvdq, cppvdq s1a/269d, pyoverdine precursor, substrate:mutant pvdq complex, hydrolase
• Biological source: Pseudomonas aeruginosa; More
• Total number of polymer chains: 1
• Total formula weight: 78838.65

Authors

Mascarenhas, R.,Catlin, D.,Wu, R.,Clevenger, K.,Fast, W.,Liu, D. (deposition date: 2016-12-20, release date: 2017-03-01, Last modification date: 2019-11-27)

• Primary citation: Mascarenhas, R.,Clevenger, K.,Catlin, D.,Wu, R.,Fast, W.,Liu, D.; Circular Permutation Reveals a Chromophore Precursor Binding Pocket of the Siderophore Tailoring Enzyme PvdQ; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.55 Å)