5UAK

Dephosphorylated, ATP-free human cystic fibrosis transmembrane conductance regulator (CFTR)

Replaces:  5U71

Summary for 5UAK

• Entry DOI: 10.2210/pdb5uak/pdb
• Related: 5UAR
• EMDB information: 8461 8516
• Descriptor: Cystic fibrosis transmembrane conductance regulator (2 entities in total)
• Functional Keywords: abc transporter, anion channel, cystic fibrosis, membrane protein, hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Early endosome membrane ; Multi-pass membrane protein : P13569
• Total number of polymer chains: 2
• Total formula weight: 170988.58

Authors

Liu, F.,Zhang, Z.,Chen, J. (deposition date: 2016-12-19, release date: 2017-01-18, Last modification date: 2024-03-06)

• Primary citation: Liu, F.,Zhang, Z.,Csanady, L.,Gadsby, D.C.,Chen, J.; Molecular Structure of the Human CFTR Ion Channel.; Cell, 169:85-95.e8, 2017; PubMed: 28340353; DOI: 10.1016/j.cell.2017.02.024

Experimental method

ELECTRON MICROSCOPY (3.87 Å)