5U9I

Crystal structure of the FKBP domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) complexed with S-farnesyl-L-cysteine methyl ester

5U9I の概要

• エントリーDOI: 10.2210/pdb5u9i/pdb
• 関連するPDBエントリー: 5U9A 5U9J 5U9K
• 分子名称: Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1), FARNESYL (2 entities in total)
• 機能のキーワード: aipl1, fkbp, chaperone, pde6, photoreceptor, lca, isoprenyl, signaling protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 19533.48

構造登録者

Yadav, R.P.,Gakhar, L.,Liping, Y.,Artemyev, N.O. (登録日: 2016-12-16, 公開日: 2017-07-26, 最終更新日: 2023-10-04)

• 主引用文献: Yadav, R.P.,Gakhar, L.,Yu, L.,Artemyev, N.O.; Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.; Proc. Natl. Acad. Sci. U.S.A., 114:E6536-E6545, 2017; PubMed: 28739921; DOI: 10.1073/pnas.1704782114

実験手法

X-RAY DIFFRACTION (2.3 Å)