5U98

The crystal structure of a self-peptide complexed to Abacavir and HLA-B*57:01

5U98 の概要

• エントリーDOI: 10.2210/pdb5u98/pdb
• 分子名称: HLA class I histocompatibility antigen, B-57 alpha chain, Beta-2-microglobulin, VAL-THR-THR-ASP-ILE-GLN-VAL-LYS-VAL, ... (5 entities in total)
• 機能のキーワード: mhc, antigen presenting cell, t-cell receptor, human leukocyte antigen, drug hypersensitivity, abacavir hypersensitivity, repertoire-altering small molecule, immune response, immunoglobulin-like beta-sandwich, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 89810.05

構造登録者

Ostrov, D.A.,Bracey, A.W.,Pompeu, Y.A.,Jakoncic, J.,Buus, S.,Buus, A.S.,Schutte, R.J. (登録日: 2016-12-15, 公開日: 2017-07-19, 最終更新日: 2023-10-04)

• 主引用文献: Yerly, D.,Pompeu, Y.A.,Schutte, R.J.,Eriksson, K.K.,Strhyn, A.,Bracey, A.W.,Buus, S.,Ostrov, D.A.; Structural Elements Recognized by Abacavir-Induced T Cells.; Int J Mol Sci, 18:-, 2017; PubMed: 28686208; DOI: 10.3390/ijms18071464

実験手法

X-RAY DIFFRACTION (2 Å)