5U5C

Coiled Coil Peptide Metal Coordination Framework: Tetramer Fold

Summary for 5U5C

Entry DOI	10.2210/pdb5u5c/pdb
Related	5U59 5U5A 5U5B
Descriptor	Designed tetrameric coiled coil peptide with one terpyridine side chain, COPPER (II) ION, HEXANE-1,6-DIOL, ... (4 entities in total)
Functional Keywords	designed peptide, synthetic, metal coordination framework, supramolecular assembly, de novo protein
Biological source	synthetic construct
Total number of polymer chains	6
Total formula weight	20380.87
Authors	Tavenor, N.A.,Murnin, M.J.,Horne, W.S. (deposition date: 2016-12-06, release date: 2017-02-22, Last modification date: 2024-11-20)
Primary citation	Tavenor, N.A.,Murnin, M.J.,Horne, W.S. Supramolecular Metal-Coordination Polymers, Nets, and Frameworks from Synthetic Coiled-Coil Peptides. J. Am. Chem. Soc., 139:2212-2215, 2017 Cited by PubMed Abstract: Metal coordination and peptide-directed self-assembly are two proven methods for creating defined supramolecular architectures. Here, we report a new class of crystalline materials based on coiled-coil peptides bearing unnatural metal-chelating terpyridine moieties. High-resolution structural characterization of lattices formed in the presence of Cu reveals a general assembly mechanism. Subtle sequence variation in the modular synthetic ligand dictates assembly morphology. PubMed: 28161945 DOI: 10.1021/jacs.7b00651 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation