5U59

Coiled Coil Peptide Metal Coordination Framework: Dimer Fold Grown with Citrate

Summary for 5U59

Entry DOI	10.2210/pdb5u59/pdb
Related	5U5A 5U5B 5U5C
Descriptor	Designed dimeric coiled coil peptide with two terpyridine side chains, COPPER (II) ION, CITRIC ACID, ... (4 entities in total)
Functional Keywords	designed peptide, synthetic, metal coordination framework, supramolecular assembly, de novo protein
Biological source	synthetic construct
Total number of polymer chains	1
Total formula weight	4095.51
Authors	Tavenor, N.A.,Murnin, M.J.,Horne, W.S. (deposition date: 2016-12-06, release date: 2017-02-22, Last modification date: 2024-10-16)
Primary citation	Tavenor, N.A.,Murnin, M.J.,Horne, W.S. Supramolecular Metal-Coordination Polymers, Nets, and Frameworks from Synthetic Coiled-Coil Peptides. J. Am. Chem. Soc., 139:2212-2215, 2017 Cited by PubMed Abstract: Metal coordination and peptide-directed self-assembly are two proven methods for creating defined supramolecular architectures. Here, we report a new class of crystalline materials based on coiled-coil peptides bearing unnatural metal-chelating terpyridine moieties. High-resolution structural characterization of lattices formed in the presence of Cu reveals a general assembly mechanism. Subtle sequence variation in the modular synthetic ligand dictates assembly morphology. PubMed: 28161945 DOI: 10.1021/jacs.7b00651 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation