5U3T

Human PPARdelta ligand-binding domain in complexed with specific agonist 4

5U3T の概要

• エントリーDOI: 10.2210/pdb5u3t/pdb
• 分子名称: Peroxisome proliferator-activated receptor delta, 6-[2-({(propan-2-yl)[4-(thiophen-3-yl)benzene-1-carbonyl]amino}methyl)phenoxy]hexanoic acid, heptyl beta-D-glucopyranoside, ... (7 entities in total)
• 機能のキーワード: ppardelta, ligand-binding domain, agonist, protein binding-activator complex, protein binding/activator
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 65340.22

構造登録者

Wu, C.-C.,Baiga, T.J.,Downes, M.,La Clair, J.J.,Atkins, A.R.,Richard, S.B.,Stockley-Noel, T.A.,Bowman, M.E.,Evans, R.M.,Noel, J.P. (登録日: 2016-12-03, 公開日: 2017-03-22, 最終更新日: 2023-10-04)

• 主引用文献: Wu, C.C.,Baiga, T.J.,Downes, M.,La Clair, J.J.,Atkins, A.R.,Richard, S.B.,Fan, W.,Stockley-Noel, T.A.,Bowman, M.E.,Noel, J.P.,Evans, R.M.; Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.; Proc. Natl. Acad. Sci. U.S.A., 114:E2563-E2570, 2017; PubMed: 28320959; DOI: 10.1073/pnas.1621513114

実験手法

X-RAY DIFFRACTION (1.7 Å)