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5TZ6

Crystal Structure of CurJ Dehydratase H978F Inactive Mutant In Complex with Compound 21

Summary for 5TZ6
Entry DOI10.2210/pdb5tz6/pdb
Related5TZ5 5TZ7
DescriptorCurJ, (2E,5R)-5-hydroxy-2-methylhept-2-enoic acid (3 entities in total)
Functional Keywordsdehydratase, curacin, polyketide synthase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological sourceMoorea producens 3L
Total number of polymer chains2
Total formula weight69326.17
Authors
Dodge, G.J.,Smith, J.L. (deposition date: 2016-11-21, release date: 2017-01-11, Last modification date: 2023-10-04)
Primary citationFiers, W.D.,Dodge, G.J.,Sherman, D.H.,Smith, J.L.,Aldrich, C.C.
Vinylogous Dehydration by a Polyketide Dehydratase Domain in Curacin Biosynthesis.
J. Am. Chem. Soc., 138:16024-16036, 2016
Cited by
PubMed: 27960309
DOI: 10.1021/jacs.6b09748
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

217705

数据于2024-03-27公开中

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