5TP3
Crystal structure of the RSV-neutralizing single-domain antibody F-VHH-4
Summary for 5TP3
Entry DOI | 10.2210/pdb5tp3/pdb |
Descriptor | F-VHH-4 (2 entities in total) |
Functional Keywords | nanobody, respiratory syncytial virus, ig fold, fusion glycoprotein, pseudomerohedral, immune system |
Biological source | Lama glama (llama) |
Total number of polymer chains | 2 |
Total formula weight | 27216.16 |
Authors | Wrapp, D.,Gilman, M.S.A.,McLellan, J.S. (deposition date: 2016-10-19, release date: 2017-02-22, Last modification date: 2023-10-04) |
Primary citation | Rossey, I.,Gilman, M.S.,Kabeche, S.C.,Sedeyn, K.,Wrapp, D.,Kanekiyo, M.,Chen, M.,Mas, V.,Spitaels, J.,Melero, J.A.,Graham, B.S.,Schepens, B.,McLellan, J.S.,Saelens, X. Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. Nat Commun, 8:14158-14158, 2017 Cited by PubMed: 28194013DOI: 10.1038/ncomms14158 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.874 Å) |
Structure validation
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