5TOV

Crystal structure of the inactive form of S-adenosyl-L-homocysteine hydrolase from Thermotoga maritima in binary complex with NADH

5TOV の概要

• エントリーDOI: 10.2210/pdb5tov/pdb
• 分子名称: Adenosylhomocysteinase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: regulation of sam-dependent methylation reactions, hydrolase
• 由来する生物種: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 91094.04

構造登録者

Czyrko, J.,Brzezinski, K. (登録日: 2016-10-19, 公開日: 2017-07-05, 最終更新日: 2024-01-17)

• 主引用文献: Brzezinski, K.,Czyrko, J.,Sliwiak, J.,Nalewajko-Sieliwoniuk, E.,Jaskolski, M.,Nocek, B.,Dauter, Z.; S-adenosyl-L-homocysteine hydrolase from a hyperthermophile (Thermotoga maritima) is expressed in Escherichia coli in inactive form - Biochemical and structural studies.; Int. J. Biol. Macromol., 104:584-596, 2017; PubMed: 28629859; DOI: 10.1016/j.ijbiomac.2017.06.065

実験手法

X-RAY DIFFRACTION (1.9 Å)