5TIY
Schistosoma haematobium (Blood Fluke) Sulfotransferase/S-oxamniquine Complex
Summary for 5TIY
Entry DOI | 10.2210/pdb5tiy/pdb |
Related | 5TIV 5TIW 5TIX 5TIZ |
Descriptor | Sulfotransferase, ADENOSINE-3'-5'-DIPHOSPHATE, {(2S)-7-nitro-2-[(propan-2-ylamino)methyl]-1,2,3,4-tetrahydroquinolin-6-yl}methanol, ... (4 entities in total) |
Functional Keywords | sulfotransferase, parasite, helminth, oxamniquine, transferase |
Biological source | Schistosoma haematobium (Blood fluke) |
Total number of polymer chains | 1 |
Total formula weight | 29969.10 |
Authors | Taylor, A.B.,Hart, P.J. (deposition date: 2016-10-03, release date: 2017-05-31, Last modification date: 2023-10-04) |
Primary citation | Taylor, A.B.,Roberts, K.M.,Cao, X.,Clark, N.E.,Holloway, S.P.,Donati, E.,Polcaro, C.M.,Pica-Mattoccia, L.,Tarpley, R.S.,McHardy, S.F.,Cioli, D.,LoVerde, P.T.,Fitzpatrick, P.F.,Hart, P.J. Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy. J. Biol. Chem., 292:11154-11164, 2017 Cited by PubMed: 28536265DOI: 10.1074/jbc.M116.766527 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.76 Å) |
Structure validation
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