5TIJ

Structure of Human Enolase 2 with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonate (purified enantiomer)

5TIJ の概要

• エントリーDOI: 10.2210/pdb5tij/pdb
• 分子名称: Gamma-enolase, ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: enolase gamma, glycolysis, neuron specific enolase, carbohydrate metabolism, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 96769.37

構造登録者

Leonard, P.G.,Muller, F.L. (登録日: 2016-10-03, 公開日: 2017-10-18, 最終更新日: 2023-10-04)

• 主引用文献: Lin, Y.H.,Satani, N.,Hammoudi, N.,Ackroyd, J.J.,Khadka, S.,Yan, Y.C.,Georgiou, D.K.,Sun, Y.,Zielinski, R.,Tran, T.,Castro Pando, S.,Wang, X.,Maxwell, D.,Peng, Z.,Pisaneschi, F.,Mandal, P.J.,Leonard, P.G.,Xu, Q.,Wu, Q.,Jiang, Y.,Czako, B.,Kang, Z.,Asara, J.M.,Priebe, W.,Bornmann, W.,Marszalek, J.R.,DePinho, R.A.,Muller, F.L.; Eradication of ENO1-deleted Glioblastoma through Collateral Lethality; Biorxiv, 2019; DOI: 10.1101/331538

実験手法

X-RAY DIFFRACTION (2.634 Å)