5T5F

Neisseria meningitidis factor H binding protein in complex with monoclonal antibody JAR5

Summary for 5T5F

Entry DOI	10.2210/pdb5t5f/pdb
Descriptor	Factor H binding protein variant B24, Monoclonal antibody Jar5 heavy chain, Monoclonal antibody Jar5 light chain, ... (4 entities in total)
Functional Keywords	fhbp, jar5, epitope mapping, monoclonal antibody, cooperativity, neisseria meningitidis, protein binding
Biological source	Neisseria meningitidis More
Total number of polymer chains	3
Total formula weight	73908.72
Authors	Malito, E. (deposition date: 2016-08-30, release date: 2016-11-09, Last modification date: 2024-01-17)
Primary citation	Malito, E.,Lo Surdo, P.,Veggi, D.,Santini, L.,Stefek, H.,Brunelli, B.,Luzzi, E.,Bottomley, M.J.,Beernink, P.T.,Scarselli, M. Neisseria meningitidis factor H-binding protein bound to monoclonal antibody JAR5: implications for antibody synergy. Biochem. J., 473:4699-4713, 2016 Cited by PubMed: 27784765 DOI: 10.1042/BCJ20160806 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.98 Å)

Structure validation