5T3D
Crystal structure of holo-EntF a nonribosomal peptide synthetase in the thioester-forming conformation
Replaces: 4ZXJSummary for 5T3D
Entry DOI | 10.2210/pdb5t3d/pdb |
Descriptor | Enterobactin synthase component F, 5'-({[(2R,3S)-3-amino-4-hydroxy-2-{[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}butyl]sulfonyl}amino)-5'-deoxyadenosine (3 entities in total) |
Functional Keywords | nonribosomal peptide synthetase, nrps, condensation, adenylation, pcp, thioesterase, phosphopantetheine, biosynthetic protein |
Biological source | Escherichia coli (strain K12) |
Total number of polymer chains | 1 |
Total formula weight | 143087.04 |
Authors | Miller, B.R.,Drake, E.J.,Sundlov, J.A.,Gulick, A.M. (deposition date: 2016-08-25, release date: 2016-09-21, Last modification date: 2019-12-25) |
Primary citation | Drake, E.J.,Miller, B.R.,Shi, C.,Tarrasch, J.T.,Sundlov, J.A.,Allen, C.L.,Skiniotis, G.,Aldrich, C.C.,Gulick, A.M. Structures of two distinct conformations of holo-non-ribosomal peptide synthetases. Nature, 529:235-238, 2016 Cited by PubMed: 26762461DOI: 10.1038/nature16163 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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