5T0B

Crystal structure of H6 hemagglutinin G225D mutant from Taiwan (2013) H6N1 influenza virus in complex with 6'-SLN

Summary for 5T0B

• Entry DOI: 10.2210/pdb5t0b/pdb
• Related PRD ID: PRD_900046
• Descriptor: Hemagglutinin, Hemagglutinin HA2 chain, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: influenza virus, hemagglutinin, ha, taiwan (2013) h6n1, receptor specificity, immune system
• Biological source: H6N1 subtype; More
• Total number of polymer chains: 6
• Total formula weight: 175843.79

Authors

Wilson, I.A.,Tzarum, N.,Zhu, X. (deposition date: 2016-08-15, release date: 2017-06-14, Last modification date: 2023-10-04)

• Primary citation: de Vries, R.P.,Tzarum, N.,Peng, W.,Thompson, A.J.,Ambepitiya Wickramasinghe, I.N.,de la Pena, A.T.T.,van Breemen, M.J.,Bouwman, K.M.,Zhu, X.,McBride, R.,Yu, W.,Sanders, R.W.,Verheije, M.H.,Wilson, I.A.,Paulson, J.C.; A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors.; EMBO Mol Med, 9:1314-1325, 2017; PubMed: 28694323; DOI: 10.15252/emmm.201707726

Experimental method

X-RAY DIFFRACTION (2.001 Å)