5SYZ
Human Liver Receptor Homologue-1 (LRH-1) Bound to a RJW100 stereoisomer and a Fragment of TIF-2
Summary for 5SYZ
Entry DOI | 10.2210/pdb5syz/pdb |
Descriptor | Nuclear receptor subfamily 5 group A member 2, Nuclear receptor coactivator 2, (1S,3aR,6aR)-5-hexyl-4-phenyl-3a-(1-phenylethenyl)-1,2,3,3a,6,6a-hexahydropentalen-1-ol, ... (4 entities in total) |
Functional Keywords | nuclear receptor, agonist, coactivator, nuclear protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 30169.84 |
Authors | Ortlund, E.A.,Mays, S.G. (deposition date: 2016-08-12, release date: 2016-10-12, Last modification date: 2023-10-04) |
Primary citation | Mays, S.G.,Okafor, C.D.,Whitby, R.J.,Goswami, D.,Stec, J.,Flynn, A.R.,Dugan, M.C.,Jui, N.T.,Griffin, P.R.,Ortlund, E.A. Crystal Structures of the Nuclear Receptor, Liver Receptor Homolog 1, Bound to Synthetic Agonists. J. Biol. Chem., 291:25281-25291, 2016 Cited by PubMed: 27694446DOI: 10.1074/jbc.M116.753541 PDB entries with the same primary citation |
Experimental method |
Structure validation
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